Purine nucleosides
Medchemexpress LLC 2'-Deoxyguanosine (standard) | 961-07-9 | MFCD00080300 | 99.2% | 267.24 | 50 MG
2'-Deoxyguanosine (Standard) is the analytical standard for 2'-Deoxyguanosine. It is intended for research and analytical applications. This purine nucleoside exhibits diverse biological activities, including inducing DNA division in mouse thymus cells and acting as a potent cell division inhibitor in plant cells. In vitro, it inhibits the clonal growth of HL-60 and K562 leukemia cells with IC50 values of 50 and 80 μM, respectively.
- Analytical standard for 2'-deoxyguanosine
- Intended for research and analytical applications
- Induces DNA division in mouse thymus cells
- Potent cell division inhibitor in plant cells
- Inhibits clonal growth of HL-60 and K562 leukemia cells
- Used in qualitative, quantitative, and methodological research experiments
- Suitable for HPLC, GC, and MS applications
Sigma Aldrich Fine Chemicals Biosciences MCOPPB trihydrochloride hydrate >98% (HPLC) | Purity: >98% (HPLC) | 1028969-49-4 (free base) | 25MG
MCOPPB trihydrochloride hydrate >98% (HPLC) | Purity: >98% (HPLC) | 1028969-49-4 (free base) | 25MG
Cambridge Isotope Laboratories 2-Fluoro-2-deoxyguanosine 5-triphosphate ammonium salt (unlabeled) (in solution) CP 90% 100 umol
2-Fluoro-2-deoxyguanosine 5-triphosphate ammonium salt (unlabeled) (in solution) CP 90% 100 umol
Medchemexpress LLC 2'-Deoxyadenosine monohydrate-13C10,15N5 hydrate | 2483830-27-7 | 99.7% | 284.15 | 1 MG
2'-Deoxyadenosine monohydrate-13C10,15N5 hydrate | 2483830-27-7 | 99.7% | 284.15 | 1 MG
Innovative Research Inc Imprtn A2 RcmbPrtn N6 Htag
Human Importin alpha 2 Recombinant Protein N-6 His Tag 50UG - Human Importin alpha 2 Recombinant Protein N-6 His Tag is produced in E. coli. This is a Liquid protein buffered in a 0.2 um filtered solution of 20mM TrisHCl,1mM DTT,20% Glycerol, pH 8.0 . It is not recommended to reconstitute to a concentration less than 100UG/ml. with a purity of greater than 95% per reducing SDS-PAGE.Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.Karyopherin Subunit alpha-2 (KPNA2) belongs to the importin alpha family. KPNA2 is widely expressed in many tissues and contains an N-terminal hydrophilic region, a hydrophobic central region composed of 10 repeats, and a short hydrophilic C-terminal. KPNA2 interacts with the NLSs of DNA helicase Q1 and SV40 T antigen and may be involved in the nuclear transport of proteins. KPNA2 also may play a role in V(D)J recombination.KPNA2 functions in nuclear protein importantly as an adapter protein for nuclear receptor KPNB1 For RUO.
Medchemexpress LLC 2'-Deoxyadenosine-5'-triphosphate-13C10 dilithium | 1927-31-7 | 95.0% | 512.97 | 1 MG
2'-Deoxyadenosine-5'-triphosphate-13C10 dilithium (dATP-13C10 dilithium) is a 13C-labeled version of 2'-Deoxyadenosine-5'-triphosphate (dATP). dATP is a nucleotide crucial for DNA synthesis or replication in cells, serving as a substrate for DNA polymerase.
- Used as a tracer
- Used as an internal standard for quantitative analysis
- Suitable for analysis by NMR
- Suitable for analysis by GC-MS
- Suitable for analysis by LC-MS
Medchemexpress LLC Malvidin-3-O-arabinoside chloride | 28500-04-1 | 97.1% | 498.86 | 5 MG
Malvidin-3-O-arabinoside chloride (M3A chloride) is a research chemical that ameliorates ethyl carbamate-induced oxidative damage by stimulating AMPK-mediated autophagy. It is used in studies to understand cellular processes related to oxidative stress and autophagy.
- Stimulates phosphorylation of AMP-activated protein kinase (AMPK)
- Upregulates LAMP-1 expression
- Restores lysosomal acidity and strengthens lysosomal functions
- Inhibits excess reactive oxygen species (ROS) generation
- Enhances glutathione (GSH) levels and autophagy flux
- Upregulates LC3-II/LC3-I ratio
Cayman Chemical N6-benzoyl-2-DeoxyadenosIn 1g
A nucleoside building block; has been used in the synthesis of various oligonucleotides
Sigma Aldrich Fine Chemicals Biosciences 2'-Deoxyguanosine monohydrate 99-100% | 312693-72-4 | MFCD00150760 | 25MG
2'-Deoxyguanosine monohydrate 99-100% | Purity: 99-100% | Mol Wt: 285.26 | 312693-72-4 | MFCD00150760 | 25MG
Biotium Primary Antibody CA15 3 CD227 EMA MUC1 VU-4H5 CF740 1/EA
MAb VU-4H5 reacts with MUC1 a large transmembrane glycoprotein expressed on the ductal surface of normal glandular epithelia The dominant epitope of MAb VU4H5 is APDTR as established with epitope fingerprinting VU-4H5 preferentially binds to under-glycosylated tumor MUC1 The extracellular domain of MUC1 largely consists of a highly conserved O-glycosylated 20 amino acids tandem repeat which can occur 30-100 times per molecule depending on the length of the allele involved In the vast majority of human carcinomas this protein is upregulated and poorly glycosylated and appears on the cell surface in a non-polarized fashion Antibody to EMA is useful as a pan-epithelial marker for detecting early metastatic loci of carcinoma in bone marrow or liver
Medchemexpress LLC 6-Thio-2'-deoxyguanosine | 789-61-7 | 99.7% | 283.31 | 10 MG
6-Thio-2'-Deoxyguanosine is a nucleoside analogue that can be incorporated into de novo-synthesized telomeres by telomerase. This compound has shown rapid cell death in various cancer cell lines with IC50 values between 0.7-2.9 μM. In A549 lung cancer cell-based mouse xenograft studies, it decreased tumor growth rate, outperforming 6-thioguanine treatment, and increased telomere dysfunction in tumor cells in vivo. It is for research use only.
- Nucleoside analogue
- Incorporated into de novo-synthesized telomeres by telomerase
- Induces rapid cell death in various cancer cell lines
- Decreases tumor growth rate in mouse xenograft studies
- Increases telomere dysfunction in tumor cells in vivo