Purine nucleosides
Apexbio Technology LLC 2-Deoxyadenosine-monoH2O
2 -Deoxyadenosine monohydrate (CAS No 16373-93-6) is widely used in biomedical research particularly in molecular biology and pharmacology studies This compound originates from the deoxyribonucleic acid (DNA) and acts by integrating into DNA strands impacting replication and cellular processes It targets pathways involved in nucleoside metabolism and DNA synthesis In vitro it demonstrates activity typically in the nanomolar to low micromolar range making it valuable for studying DNA replication and repair mechanisms Common applications include cell-based assays animal studies and drug screening to investigate its effects on cellular proliferation and apoptosis Experimental concentrations typically depend on the specific research design
Biotium MUC1 / CA15-3 / EMA / CD227 (Epithelial Marker)(VU-4H5), CF740 conjugate, 0.1mg/mL
MAb VU-4H5 reacts with MUC1, a large transmembrane glycoprotein expressed on the ductal surface of normal glandular epithelia. The dominant epitope of MAb VU4H5 is APDTR as established with 'epitope fingerprinting'. VU-4H5 preferentially binds to under-glycosylated 'tumor' MUC1. The extracellular domain of MUC1 largely consists of a highly conserved, O-glycosylated 20 amino acids tandem repeat which can occur 30-100 times per molecule depending on the length of the allele involved. In the vast majority of human carcinomas this protein is upregulated and poorly glycosylated and appears on the cell surface in a non-polarized fashion. Antibody to EMA is useful as a pan-epithelial marker for detecting early metastatic loci of carcinoma in bone marrow or liver.
Medchemexpress LLC 2'-deoxyadenosine | 958-09-8 | MFCD00005754 | 251.24 g/mol | C10H13N5O3 | 500 MG
2'-deoxyadenosine is an adenine nucleoside supplied for research and analytical applications. The compound has been reported to inhibit glucose-stimulated insulin release, activate caspase-3 and promote apoptosis, and inhibit S-adenosyl-L-homocysteine hydrolase (SAHH).
- Adenine nucleoside for research applications.
- Modulates insulin-stimulated cAMP accumulation and insulin release.
- Promotes apoptosis via caspase-3 activation.
- Inhibits S-adenosyl-L-homocysteine hydrolase (SAHH).
- Available from suppliers in small research quantities (supplier pack indicated as 500 MG in provided row data).
Genscript Corporation CA15-3 AntibodyA5D8 mAb Mo
CA15-3 (Carcinoma antigen 15-3) is also known as MUC 1 antigen It is a membrane-anchored mucin-type glycoprotein present in malignant cells It is used as tumor marker to monitor breast cancer treatment and disease recurrence
Medchemexpress LLC 8-Bromo-2'-deoxyadenosine | 14985-44-5 | ≥98.0% | 330.14 | 50 MG
8-Bromo-2'-deoxyadenosine is a purine nucleoside analog. These analogs possess broad antitumor activity, specifically targeting indolent lymphoid malignancies. Their anticancer mechanisms involve inhibiting DNA synthesis and inducing apoptosis.
- Purine nucleoside analog
- Has broad antitumor activity
- Targets indolent lymphoid malignancies
- Inhibits DNA synthesis
- Induces apoptosis
Sigma Aldrich Fine Chemicals Biosciences 5-Deoxyadenosine methylthi25MG
5-Deoxyadenosine methylthi25MG
Cambridge Isotope Laboratories 2-Deoxyguanosine 5-triphosphate ammonium salt (13C10 98% 15N5 96-98%) CP 90% (in solution) 20 umol
2-Deoxyguanosine 5-triphosphate ammonium salt (13C10 98% 15N5 96-98%) CP 90% (in solution) 20 umol
Cambridge Isotope Laboratories 2-Deoxyguanosine 5-triphosphate ammonium salt (15N5 98-99%) CP 90% (in solution) 20 umol
2-Deoxyguanosine 5-triphosphate ammonium salt (15N5 98-99%) CP 90% (in solution) 20 umol
Medchemexpress LLC 2'-Deoxyguanosine-d13 | 961-07-9 | 99.9% | 280.32 | 5 MG
2'-Deoxyguanosine-d13 is a deuterium-labeled version of 2'-Deoxyguanosine. It is intended for research use only and can be utilized as a tracer or as an internal standard for quantitative analysis using techniques such as NMR, GC-MS, or LC-MS. Deuteration, the incorporation of stable heavy isotopes of hydrogen into drug molecules, has the potential to influence the pharmacokinetic and metabolic profiles of drugs.
- Used as a tracer.
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC N6-Methyladenine 10mM 1mL | 443-72-1 | 1 ML
N6-methyladenine is a methylated form of the nucleobase adenine used as an analytical standard and research reagent for studies of DNA/RNA methylation and bacterial epigenetics. It is supplied as a ready-to-use 10 mM solution in DMSO (1 mL) and is also available as solids for reconstitution.
- Ready-to-use 10 mM solution in DMSO, 1 mL.
- Also available as solid material for reconstitution.
- High purity (98.8%).
- Molecular formula C6H7N5 and molecular weight 149.16 g/mol.
- Intended for research and analytical applications.
Medchemexpress LLC 2'-Deoxyadenosine-5'-triphosphate-13C10,15N5 (dilithium) | 1927-31-7 | 99.2% | 517.94 | 1 MG
2'-Deoxyadenosine-5'-triphosphate-13C10,15N5 (dATP-13C10,15N5) dilithium is a 13C and 15N-labeled nucleotide essential for DNA synthesis as a substrate of DNA polymerase. It is valuable in research as:
- Used as a tracer.
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.