Purine nucleosides
Medchemexpress LLC 2'-Deoxyadenosine monohydrate | 16373-93-6 | 99.9% | 269.26 | 50 G
2'-Deoxyadenosine monohydrate is an adenine nucleoside that inhibits glucose-stimulated insulin release. It also inhibits glucose-stimulated increases in islet cyclic AMP (cAMP) accumulation, activates caspase-3, promotes apoptosis, and inhibits the activity of S-adenosyl-L-homocysteine hydrolase (SAHH). Additionally, it inhibits the growth of various cells and exhibits an anticancer effect on colon cancer.
- Inhibits glucose-stimulated insulin release.
- Inhibits glucose-stimulated increases in islet cyclic AMP (cAMP) accumulation.
- Activates caspase-3 and promotes apoptosis.
- Inhibits the activity of S-adenosyl-L-homocysteine hydrolase (SAHH).
- Inhibits the growth of various cells.
- Has an anticancer effect on colon cancer.
Medchemexpress LLC 8-Bromo-2'-deoxyadenosine | 14985-44-5 | ≥98.0% | 330.14 | 100 MG
8-Bromo-2'-deoxyadenosine is a purine nucleoside analog. These analogs possess broad antitumor activity against indolent lymphoid malignancies. Their anticancer mechanisms involve the inhibition of DNA synthesis and the induction of apoptosis.
- Purine nucleoside analog
- Broad antitumor activity
- Inhibits DNA synthesis
- Induces apoptosis
Medchemexpress LLC Peonidin-3-O-arabinoside chloride | 524943-91-7 | 98.5% | 468.84 | 25 MG
Peonidin-3-O-arabinoside chloride is an anthocyanin that can be isolated from *Vaccinium myrtillus L.*. This chemical compound is available as a solid with high purity, suitable for various research applications.
- High purity: 98.5%
- Solid appearance
- Brown to black color
- Recommended storage at 4°C, sealed, away from moisture
- Extended storage in solvent at -80°C (6 months) or -20°C (1 month)
Medchemexpress LLC 2'-Deoxyadenosine monohydrate-13C10,15N5 hydrate | 2483830-27-7 | 99.7% | 284.15 | 1 MG
2'-Deoxyadenosine monohydrate-13C10,15N5 hydrate | 2483830-27-7 | 99.7% | 284.15 | 1 MG
Medchemexpress LLC 3′-Deoxyguanosine | 3608-58-0 | 97.0% | 267.25 | 10 MG
3′-Deoxyguanosine is a derivative of Guanosine that interacts with human purine nucleoside phosphorylase through hydrogen bonding. It demonstrates moderate displacement activity for [3H]-guanosine in rat meninges. This product is for research use only and not sold to patients.
- Derivative of guanosine
- Interacts with human purine nucleoside phosphorylase
- Useful for studying guanosine receptors
- Useful for studying purine metabolism
- Exhibits moderate displacement activity for [3H]-guanosine in rat meninges
Medchemexpress LLC 3′-Deoxyguanosine | 3608-58-0 | MFCD28041154 | 97.0% | 267.25 | 100 MG
3′-Deoxyguanosine is a derivative of Guanosine. It interacts with human purine nucleoside phosphorylase via hydrogen bonding with residues such as Glu201 and Asn243. It exhibits moderate displacement activity for [3H]-guanosine in rat meninges and is useful for studying the mechanism of guanosine receptors and purine metabolism.
- Useful for studying guanosine receptors
- Used in research on purine metabolism
- Interacts via hydrogen bonding with human purine nucleoside phosphorylase
Medchemexpress LLC 3′-Deoxyguanosine | 3608-58-0 | 97.0% | 267.25 | 25 MG
3′-Deoxyguanosine is a derivative of Guanosine. It interacts with human purine nucleoside phosphorylase through hydrogen bonding with residues like Glu201 and Asn243. This compound demonstrates moderate displacement activity for [3H]-guanosine in rat meninges and is useful for studying the mechanism of guanosine receptors and purine metabolism.
- Derivative of guanosine.
- Interacts with human purine nucleoside phosphorylase via hydrogen bonding.
- Exhibits moderate displacement activity for [3H]-guanosine in rat meninges.
- Useful for studying guanosine receptor mechanisms.
- Useful for studying purine metabolism.
- Displaces 50 nM [3H]-guanosine binding to rat brain membranes.
Medchemexpress LLC 2'-Deoxyadenosine-5'-triphosphate-13C10 dilithium | 1927-31-7 | 95.0% | 512.97 | 1 MG
2'-Deoxyadenosine-5'-triphosphate-13C10 dilithium (dATP-13C10 dilithium) is a 13C-labeled version of 2'-Deoxyadenosine-5'-triphosphate (dATP). dATP is a nucleotide crucial for DNA synthesis or replication in cells, serving as a substrate for DNA polymerase.
- Used as a tracer
- Used as an internal standard for quantitative analysis
- Suitable for analysis by NMR
- Suitable for analysis by GC-MS
- Suitable for analysis by LC-MS
Cayman Chemical 2'-Fluoro-2'-deoxyadenosine, Purity: ≥98%, CAS: 64183-27-3, 5 g
A prodrug form of 2-F-adenine; reduces mean tumor weight in an E. coli purine nucleoside phosphorylase-expressing D54 glioblastoma mouse xenograft model at 100 mg/kg
eMolecules 312693-72-4 | 2'-Deoxyguanosine monohydrate | 1g
Ambeed | 1-(2-Methoxyphenyl)-1H-imidazole-5-carboxylic acid | 100mg | 600849156 | A866307 | 762240-23-3 | MFCD25368751 | 218.212 | C11H10N2O3
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Apexbio Technology LLC 6-O-Propynyl-2-deoxyguanosine 1mg
6-O-Propynyl-2-deoxyguanosine (CAS 1640051-47-3) is a modified nucleoside featuring an alkyne functional group at the 6-position of deoxyguanosine This structural modification enables its use in bioorthogonal click chemistry reactions facilitating site-specific labeling and conjugation in nucleic acid research The alkynyl group serves as a chemical handle for copper-catalyzed azide-alkyne cycloaddition allowing researchers to attach probes or other functional molecules 6-O-Propynyl-2-deoxyguanosine is utilized for studying DNA structure dynamics and for the development of modified oligonucleotides in biochemical and molecular biology assays
Cayman Chemical N6-Methyl-2'-deoxyadenosine, Purity: ≥98%, CAS: 2002-35-9, 50 mg
A nucleoside and inducer of EPC proliferation; stimulates the proliferation of EPCs isolated from mouse fetal livers and colony formation of isolated mouse bone marrow cell-derived progenitor cells at 10 and 100 µM; accumulates along promoters and gene coding sequences in activated mouse prefrontal cortical neurons; is associated with activation at the Bdnf promoter
Innovative Research Inc Imprtn A2 RcmbPrtn N6 Htag
Human Importin alpha 2 Recombinant Protein N-6 His Tag 50UG - Human Importin alpha 2 Recombinant Protein N-6 His Tag is produced in E. coli. This is a Liquid protein buffered in a 0.2 um filtered solution of 20mM TrisHCl,1mM DTT,20% Glycerol, pH 8.0 . It is not recommended to reconstitute to a concentration less than 100UG/ml. with a purity of greater than 95% per reducing SDS-PAGE.Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.Karyopherin Subunit alpha-2 (KPNA2) belongs to the importin alpha family. KPNA2 is widely expressed in many tissues and contains an N-terminal hydrophilic region, a hydrophobic central region composed of 10 repeats, and a short hydrophilic C-terminal. KPNA2 interacts with the NLSs of DNA helicase Q1 and SV40 T antigen and may be involved in the nuclear transport of proteins. KPNA2 also may play a role in V(D)J recombination.KPNA2 functions in nuclear protein importantly as an adapter protein for nuclear receptor KPNB1 For RUO.